Dr. Pogranichniy and his research team are working on developing an effective universal DNA vaccine against influenza A virus. His recent research work was published in the journal Viral Immunology and pictures from the article were featured on the cover of the journal. The highlight of the research is: “The DNA vaccine administered intramuscularly stimulated epitope-specific immunity against two T-cell epitopes in all ten mice before the virus challenge. All vaccinated mice survived a lethal dose of virus challenge, while all mice in the challenge control group died. The DNA vaccine delivering epitopes in this study showed promising protection against influenza virus in an animal model; however, more work needs to be done in developing a universal DNA vaccine against influenza A virus.”

Currently Dr. Pogranichniy is looking for additional private or federal funding to continue his research in this area.

Huiling Wei, Stephen D. Lenz, David H. Thompson, and Roman M. Pogranichniy. Viral Immunology. August 2012, 25(4): 297-305