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MENINGOENCEPHALITIS IN PUG DOGS

A non-suppurativemeningoen-cephalitis has become well rec­ognized in Pug dogs.  This dis­ease is sporadic and affects both adolescent and mature Pug dogs.  The most common clinical signs are seizures, circling, head-pressing, blindness, opis-thotonus and rapidly progressive lethargy and ataxia.  Hemato1ogy and serum chemistry parameters are often within normallimits.  Massive necrosis and non-suppurativemeningoencephalitis is limited to the cerebral hemispheres, thus accounting for the clini­cal signs.  Bilateral cerebral lesions are often severe, ex­tensive and involve both gray and white matter.  A specific etiology has not been determined.  The disease ap­pears to occur in certain pug lineages.  A sex predilection has not been reported.  Many affected animals have been traced to a common ancestry. Recently, the disease was diag­nosed at ADDL in an10-month-old Pug dog purchased from a pet store.

Appropriate specimens should be submitted to ADDL to rule out rabies, canine distemper, canine herpes, toxop1asmosis, Neosporum camnum,encephalito-zoonosis,ethyleneglycol toxicosis and reticulosis.  Pug dog encephalitis should be considered a differential diag­nosis in animals exhibiting signs of central nervous dys-function.

Anthony J.Skowronek,DVM Pathology Graduate Student

Locations


ADDL-West Lafayette:
406 S. University
West Lafayette, IN 47907
Phone: 765-494-7440
Fax: 765-494-9181

ADDL-SIPAC
11367 E. Purdue Farm Road
Dubois, IN 47527
Phone: (812) 678-3401
Fax: (812) 678-3412

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