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Annual Report 2005-6


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Publications and *Presentations

Abraham S, Knapp DW, Cheng L, Snyder PW, Mittal SK, Bangari DS, Kinch M, Wu L, Dhariwal J, Mohammed SI (2006) Expression of EphA2 and Ephrin A-1 carcinoma of the urinary bladder.  Clinical Cancer Research  12(2): 353-60

Baloglu S, Boyle SM, Vemulapalli R, Sriranganathan N, Schurig GG, Toth TE (2005).  Mice Immune Responses to Vaccinia Virus Recombinants Expressing Listeria monocytogenes Partial Listeriolysin and Brucella abortus Ribosomal L7/L12 Protein.  Veterinary Microbiology 109(1-2): 11-17.

Bangari DS, Mittal SK (2006)  Current strategies and future directions for eluding adenoviral vector immunity.  Current Gene Therapy 6(2): 215-226.

Bangari DS, Mittal SK (2006). Development of nonhuman adenoviruses as vaccine vectors.  Vaccine 24(7): 849-62

*Bangari DS, Mittal SK (2006) Vector biodistribution, innate immunity and vector toxicity following intravenous inoculation of nonhuman adenoviral vectors in mice.  Oral abstract presented at the 9th annual meeting of the American Society of Gene Therapy, Baltimore MD, June, 2006.

Boulineau TM,  Andrews-Jones L,  Van Alstine WG: Spontaneous aortic dissection in two Border Collies.  Journal of Veterinary Diagnostic Investigation.  Accepted, (2005)

*Contreras AS,  Boyle M,  Sriranganathan N,  Vemulapalli R,  Schurig GG  (2004) Non-replicative, gamma-irradiated B. abortus vaccine strain RB51 is protective against virulent Brucella challenge in mice.  57th Brucellosis Research Conference. Nov 13-14, 2004, Chicago, IL.

Escobar J,  Van Alstine WG,  Baker DH,  Johnson RW (2004)  Decreased protein accretion in pigs with viral and bacterial pneumonia is associated with increased myostin expression in muscle.  Journal of Nutrition 134: 3047-3053.

Ferguson NH,  Couetil LL,  Hawkins JH,  Ernst C,  Sojka J,  Van Alstine WG.  Renal evaluation post-nephrectomy in two aged horses.  Journal of the American Veterinary Medical Association.  Accepted, 2005.

Gonzáles-Smith AR, Vemulapalli R, Andrews E, Oñate (2006). Evaluation of Brucella abortus DNA vaccine by expression of Cu-Zn superoxide dismutase antigen fused to IL-2.  Immunobiology 211(1-2): 65-74.

Gopalakrishnan G, Pardo I, Vemireddi V, Ramos-Vara JA, Johnson GD (2005).  Esophagitis in camelids: report of three cases.  56th Annual Meeting of the American College of Veterinary Pathologists.  Boston, Mass.  Veterinary Pathology 42: 694

*Gulani J, Bangari D, Sanakkayala N, Mittal S, Wu CC, Vemulapalli R. Protective role of immune responses specific to antigen 85B of Mycobacterium avium ssp.paratuberculosis against Mycobacterium avium ssp avium challenge in mouse models.  106th General Meeting, American Society for Microbiology.  Orlando, FL. May, 2006.

Hoelscher MA, Garg S, Bangari DS, Besler JA, Xiuhua L, Stephenson I, Bright RA, Katz JM, Mittal SK, Sambhara S (2006).  Development of adenoviral-vector-based pandemic  influenza vaccine against antigenically distinct human H5N1 strains in mice.  Lancet 11;367 (9509): 475-81.

Hooser SB (2004)  Tremorgenic Toxins; Mycotoxicosis-Deoxynivalenol.  In: The 5-Minute Veterinary Consult, Canine and Feline. (L Tilley and F Smith, eds.) Lippincott, Williams & Wilkins, Baltimore, MD.

*Hoppe, Chris.  Miller MA,  Smith A,  Ramos-Vara JA.    Bronchopneumonia in a rat.  Case #41.   Midwest Association of Veterinary Pathologists. Augusta MI.  August, 2004

Irizarry-Rovira A, Wolf A, Ramos-Vara JA  2006  Cutaneous melanophoroma in a green iguana (Iguana iguana).  Veterinary Clinical Pathology 31: 101-105.

Kiupel M,  Webster J,  Ramos-Vara JA et al. (2004)  Microscopic grading of canine cutaneous mast cell tumors: A multi-institutional review.  Veterinary Pathology 41:476.  55th annual meeting, ACVP, Orlando, FL.

Kiupel M, Stevenson GW, Galbreath EJ, North A, HogenEsch H, Mittal SK (October 31, 2005)  Porcine Circovirus type 2 (PCV2) causes apoptosis in experimentally inoculated BALB/c mice.  BMC Vet Res, 1:7.

Kottwitz JJ,  Preziosi DE,  Miller MA,  Ramos-Vara JA,  Maggs DJ,  Bonagura JD (2004)  Heart failure caused by toxoplasmosis in a Fennec fox (Fennecus zerda).  Journal of the American Animal Hospital Association 40: 501-507.

*Langohr IM, Ramos-Vara JA, Miller MA.   Análise algoritmica no diagnóstico de tumores cutâneos de células redondas. Diagnostic Immunohistochemistry of cutaneous round cell tumors.  XII Encontro Nacional de Patologia Veterinaria.  Belo Horizonte Brazel (International). Arq. Brasil. Med. Vet. Zootec 57 (supl 1):96. July, 2005

*Langohr IM, Ramos-Vara JA, Wu CC, Froderman SF.   Listeric meningoencephalitis in a cougar (Felis concolor).  48th Annual Meeting of the American Association of Veterinary Laboratory Diagnosticians.  Hershey, PA. (National) November, 2005

Langohr IM, Tanabe M (2005) Idiopathic Complex Polysaccharide Storage Disease in an Abyssinian cat.  Veterinary Pathology 42: 502-506.

Larson, RL,  Miller RB,  Kleiboeker SB,  Miller MA,  White BJ  (2005)  Economic costs associated with two testing strategies for screening feeder calves for persistent infection with bovine viral diarrhea virus.  Journal of the American Veterinary Medical Association 226: 249-254.

Lekcharoensuk P, Lager KM, Vemulapalli R, Woodruff M, Vincent AL, Richt JA (2006).  Novel Swine Influenza Virus Subtype H3N1, United States.  Emerging Infectious Diseases 12(5): 787-794.

McFarlane D, Miller L, Craig L, Dybdal N, Habecker P, Miller MA, Patterson J, Cribb A  (2005)  Discordance in histological assessment of the pituitary pars intermedia in aged horses.  American Journal of Veterinary Research. In Press.

*Maratea KA, Ramos-Vara JA.   Spinal cord white matter: demyelinization, degenerative myelopathy.  12th annual  American Association of Zoo Veterinarians Zoo and Wildlife Pathology Workshop.  Omaha, NE (National) 2005

Miller MA, Aper RL, Fauber A, Blevins W, Ramos-Vara JA (2006)  Extraskeletal osteosarcoma associated with a retained surgical sponge in a dog.  Journal of Diagnostic Investigation 18:224-228.

*Miller MA, Aper RL, Fauber A, Blevins W, Ramos-Vara JA (2006)  Extraskeletal osteosarcoma associated with a retained surgical sponge in a dog.  Midwest Association of Veterinary Pathologists, Madison, Wisc, August, 2005

Miller MA, Ramos-Vara JA.  Glioma in a dog (Mystery slide seminar, neuropathology).  56th Annual Meeting of the American College of Veterinary Pathologists.  Boston, Mass (National) December, 2005.

*Miller MA, Ramos-Vara JA, Raper RL, Fauer A, Blevins W.  Canine extraskeletal osteosarcoma arising in a surgical sponge (textiloma).  Case #14. 24th Midwest Association of Veterinary Pathologists annual meeting. Madison, WI (Regional) August, 2005

Miller MA, Ramos-Vara JA,  Kleiboeker SB, Larson RL (2005)  Effect of delayed or prolonged fixation on immunohistochemical detection of bovine viral diarrhea virus type 1 in skin of two persistently infected calves.  Journal of Veterinary Diagnostic Investigation 17:461-463..

*Miller MA, Ramos-Vara JA, Kleiboeker SB, Larson RL.  Effect of delayed or prolonged fixation on immunohistochemical detection of bovine viral diarrhea virus in ear-notch biopsies.  47th annual meeting of the American Association of Veterinary Laboratory Diagnosticians, Greensboro, NC. October, 2004.

*Miller MA, Ramos-Vara JA, Sharma A, Smith JR.   Hepatotoxicosis and copper accumulation in a Labrador Retriever alter carprofen therapy. 47th annual meeting of the American Association of Veterinary Laboratory Diagnosticians.  Greensboro, NC. October, 2004

*Miller MA, Ramos-Vara JA, Thomsen C (2005). Metastatic transitional cell carcinoma (Mystery slide seminar, bone and joint pathology).  56th Annual Meeting of the American College of Veterinary Pathologists.  Boston, Mass. (National)

Miller, MA, Ramos-Vara JA, Yu J (2005).  Glioblastoma multiforme/anaplastic oligodendroglioma in a boxer dog.  Neuropathology Mystery Slide Seminar.  56th annual meeting American College of Veterinary Pathologists.  Boston, MA.

*Mouser P, Ramos-Vara JA  (2005)  Bacterial panophthalmitis in a cat.  Case #07.   24th Midwest Association of Veterinary Pathologists Annual Meeting, Madison, WI. (Regional)

Mouser P, Cole A, Lin TL (2006)  Maxillary osteosarcoma in a prairie dog (Cynomys ludovicianus). Journal of Veterinary Diagnostic Investigation.  18:310-312.

*Pardo, I, Ramos-Vara JR (2005)  Pulmonary neoplasia in an alpaca (Lama pacos) Case #20.  24th Midwest Association of Veterinary Pathologists Annual Meeting.  Madison, WI (Regional)

Peters MA, Lin TL, Wu CC (2005)  Infectious bursal disease virus recovery from Vero cells transfected with RNA transcripts is enhanced by expression of the structural proteins in trans.  Arch. Virol, 150: 2183-2194.

*Pineyro PE, Quiroga MA, Cappuccio JA, Machuca MA, Ramos-Vara JA, Perfumo CJ (2006).  V Congreso de Producción Porcina del MERCOSUR.  Córdoba, Argentina (International)

*Pogranichniy RM (2005) Post Weaning Multisystemic Wasting Syndrome to determine gaps in PMWS.  Presented to National Pork Board, DesMoines, IA, October, 2005

*Pogranichniy RM (2005).  Research and Diagnostic perspective on PRRSV and PCV2 virus associated diseases.  Presented to the Indiana Association of Swine Veterinarians annual meeting. Indianapolis, IN, December 2005.

Ramamoorthy S, Lindsay DS, Schurig GG, Boyle SM, Duncan R, Vemulapalli R, Sriranganathan N (2006).  Vaccination with gamma irradiated Neospora caninum tachyzoites protects mice against acute challenge with N. caninum.  Journal of Eukaryotic Microbiology 53(2): 151-156.

*Ramos-Vara JA (2005)  Invited speaker.  Four lectures: 1)Immunohistochemistry: do not be afraid of the red, brown and blue, 2) Markers in diagnostic immunohistochemistry of neoplastic diseases, 3) Algorithm approach to the diagnosis of selected neoplastic diseases, 4) Diagnostic immunohistochemistry of infectious diseases.  I Brazilian symposium of the C.L. Davis Foundation.  Belo Horizonte, Brazil (International)

*Ramos-Vara JA (2005)  Invited speaker  Aspectos de immunohistoquímica diagnóstica en medicina veterinaria.  Diagnostic immunohistochemistry in veterinary medicine.  Congreso Nacional de Patólogos Veterinarios.  Universidad Autónoma de Tamaulipas.  Tamaulipas, Mexico (International)

Ramos-Vara JA (2004)  Book review. Introduction to Immunocytochemistry by Polak JM and Van Noorden S.  BIOS Scientific Publishers.  Veterinary Pathology 41: 537.

Ramos-Vara JA  (2004)  Painting the surgical margins of a tumor biopsy.  Purdue ADDL Diagnostic Forum.  Winter issue.

Ramos-Vara JA  (2004)  Immunohistochemistry.  Purdue ADDL Diagnostic Forum. Fall issue

*Ramos-Vara JA (2005)  Streptococcus equi pneumonia and verminous arteritis in a horse.  Case #01.  24th Midwest Association of Veterinary Pathologists Annual Meeting, Madison, WI (Regional)

Ramos-Vara JA  (2005)  Technical aspects of immunohistochemistry.  Veterinary Pathology 42: 409-430

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*Ramos-Vara JA, Garner MM, Acevedo LD, Serrato S, Parás, Juan-Sallés C (2006)  Seven cases of pheochromocytoma in New World primates.  Proceedings European Association of Zoo and Wildlife Veterinarians.  Budapest, Hungary, pp. 295-296. (International)

*Ramos-Vara JA, Miller MA (2005) Hepatopathy and necrotizing dermatitis in a horse. 48th Annual Meeting of the American Association of Veterinary Laboratory Diagnosticians. Hershey, PA (National)

*Ramos-Vara JA, Miller MA, Wu CC (2005) Nocardiosis in a cat.  48th Annual Meeting of the American Association of Veterinary Laboratory Diagnosticians.  Hershey, PA  (National)

*Ramos-Vara JA, Miller MA (2005) MUM 1 Protein: Immunohistochemical characterization in canine plasmacytomas.  48th Annual Meeting of the American Association of Veterinary Laboratory Diagnosticians.  Hershey, PA  (National)

*Ramos-Vara JA, Miller MA (2005) Comparison of two polymer-based immunohistochemical detection systems: ENVISION+T and ImmpressT. 48th annual meeting of the American Association of Veterinary Laboratory Diagnosticians.  Hershey, PA  (National)

Ramos-Vara, JA, Kuipel M, Miller MA (2005)  Veterinary diagnostic immunohistochemistry: a survey of 47 laboratories. Journal of Histotechnology 28: 19-23.

Ramos-Vara JA, Kuipel M, Miller MA  (2005)  Veterinary diagnostic immunohistochemistry: a survey of 47 laboratories.  Journal of Histotechnology 28: 19-23.

Ramos-Vara JA, MA Miller,Johnson GC. (2005).  Usefulness of thyroid transcription factor-1 immunohistochemical staining in the differential diagnosis of primary pulmonary tumors of dogs.  Veterinary Pathology 42: 315-320.

Ramos-Vara JA, MA Miller, Johnson GC: (2005).  Immunohistochemical detection of thyroid transcription factor-1 (TTF-1) in canine pulmonary tumors.  Veterinary Pathology 41: 520-523.

Ramos-Vara JA, Ojeda J, Miller MA, Draft D, Watson G (2004).  Glomerulocystic kidney disease in a Belgian Malinois dog. An ultrastructural, immunohistochemical and lectin-binding study.  Ultrastructural Patholology 28: 33-43.

Ramos-Vara JA,Loiacono CM,Williams III F (2004)  Pulmonary neoplasia in two llamas (Lama glama). Veterinary Pathology 41: 520-523.

*Ramos-Vara JA (2004)  Painting biopsy margins and immunohistochemistry for the practitioner.  Annual Fall Conference for Veterinarians and Veterinary Technicians.  Purdue University.  West Lafayette, IN.

*Ramos-Vara JA. (2004)  Cutaneous botryomycosis in a horse.  Case #11. Midwest Association of Veterinary Pathologists. Augusta, MI

*Ramos-Vara JA, Miller MA (2005) 

*Ramos-Vara JA, Miller MA, Johnson GC, Loiacono CM, Kundu M (2004)  Detection of c-Kit (CD117) on cutaneous mast cell tumors of ferrets by immunohistochemistry.  47th annual meeting of the American Association of Veterinary Laboratory Diagnosticians.  Greensboro, NC

*Ramos-Vara JA, Miller MA, Johnson GC, Loiacono CM, Kundu M (2004)  Immunohistochemical characterization of equine cutaneous mast cell tumors with an antibody to CD 117 (KIT).  55th annual meeting of the American College of Veterinary Pathologists. Orlando, FL.  Veterinary Pathology 41: 558.

*Ramos-Vara, JA, Miller M, Johnson GC, Loiacono C (2004)  Cutaneous equine mast cell tumors:  Immunohistochemical detection of tryptase.  55th annual meeting of the American College of Veterinary Pathologists, Orlando, FL.  Veterinary Pathology 41: 558.

Ruiz CD, Iemura M, Medie S, Varga P,  Van Alstine WG et al (2005)  Transcather placement of a low-profile pulmonary valve made of SIS:  A long term study in a swine model.  Journal of Thoracic Cardiovascular Surgery, Accepted (2005).

*Sanakkayala N, Gulani J, Vemulapalli R (2004)  Induction of specific mucosal and systemic immune responses by intranasal inoculation of mice with live and gamma-irradiated recombinant Brucella abortus RB51.  57th Brucellosis Research Conference. November 13-14.  Chicago, IL.

*Sanakkahala N, Gulani D, Bangari D, Mittal S, Vemulapalli R.  Expression of synthetic fusion proteins of Ebola and Lassa viruses in Brucella abortus vaccine strain RB51 and replication-defective human adenovirus serotype 5.  106th General Meeting, American society for Microbiology, Orlando, FL. May, 2006.

Sanakkayala N, Sokolovska A, Gulani J, HogenEsch H, Sriranganathan N, Boyle SM, Schrurig GG, Vemulapalli R (2005).  Induction of antigen-specific Th1-type immune responses by gamma-irradiated recombinant Brucella abortus RB51.  Clinical and diagnostic Laboratory Immunology 12(12): 1429-1436.

*Seleem, M., Sanakkayala N, Vemulapalli R, Boyle SM, Schurig GG, and Sriranganathan N (2004)  Improved expression vector for Brucella species. 57th Brucellosis Research Conference.  Nov. 13-14. Chicago, IL.

Seleem, MN., Vemulapalli R, Boyle SM, Schurig GG, and  Sriranganathan N (2004) Improved expression vector for Brucella species.  Biotechniques 37(5): 740-744.

*Sharma A, Ramos-Vara JA, Miller MA (2005)  Immunohistochemical demonstration of protein gene product 9.5 (PGP 9.5) in epitheliotropic cutaneous lymphoma (mycosis fungoides) of dogs.  56th Annual Meeting of the American College of Veterinary Pathologists. Boston, Mass.  Veterinary Pathology 42: 724.

*Soto S, Amass S, Dunham A, Guptill L,  Vemulapalli R. (2004)  Evaluation of Bartonella henselae outer membrane proteins for possible antigenic variation and comparison of immunogenic surface antigens for type I and II feline infections.  CRWAD, Nov 15-17.  Chicago, IL.

Suedmeyer, WK, Ludlow C, Layton C, Dennis J,  Miller MA (2004)  Primary lymphangiectasia in a dingo (Canis familaris dingo). Journal of Zoo Wildlife Medicine 35: 572-575.

*Thacker H. Leon (August, 2004)  "The Importance of Veterinary Diagnostic Laboratories"  Presented to the Illinois Veterinary Medical Association Diagnostic Laboratory Committee.  Springfield, IL

*Thacker H. Leon  (September, 2004)  "How TSE's can be diagnosed".  Presented at the Purdue University School of Veterinary Medicine Fall Conference for Veterinarians, West Lafayette, IN.

*Thacker H. Leon (November, 2004).  Careers in Veterinary Medicine/Diagnostic Pathology".  Presented to the Purdue University Pre-Vet Club.  West Lafayette, IN

*Thacker H. Leon  (December, 2004)  "ADDL Update". Presented at the Indiana Swine Group annual meeting.  Indianapolis , IN

*Thacker H. Leon  (March, 2005)  "Foreign Animal Disease Threats". Presented to the Agriculture Industry Studies Group, Industrial College of the Armed Forces, West Lafayette, IN.

*Thacker H. Leon  (April, 2005)   "Foreign Animal Disease Threats".  Presented to students and faculty of the Department of Sciences, Vincennes University, Vincennes, IN

Tibbetts RJ, Lin TL, Wu CC (2005) Insertional mutation of marA vitiates inducible multiple antimicrobial resistance in Salmonella enterica subsp. Enterica serovar cholerasuis.

Toepfer-Berg TL, Escobar J,  Van Alstine WG et al (2004)  Vitamin E supplementation does not mitigate the acute morbidity effects of PRRSV in nursery pigs. Journal of Animal Science 82: 1942-1951.

Vemulapalli, R., Langohr IM,  Sanchez A,  Kuipel M,  Bolin CA,  Wu CC, and  Lin TL (2005) Molecular detection of Leptospira kirschneri in tissues of a prematurely born foal.  Journal of Veterinary Diagnostic Investigation 17(1): 65-69.

Vemulapalli, R, Contreras A, Sanakkayala N, Srinanganathan N, Boyle SM and  Schurig GG (2004)  Enhanced efficacy of recombinant Brucella abortus RB51 vaccines against B. melitensis infection in mice.  Veterinary Microbiology 102 (3-4) 237-245.

*Vemulapalli R.  PRRS Virus-Biology and Current and Future Vaccinology.  93rd Annual Fall Conference for Veterinarians and Veterinary Technicians.  West Lafayette, IN. September, 2005.

Vemulapalli TH, Vemulapalli R, Schurig GG, Boyle SM, Sriranganathan N (2006).  Role in virulence of a Brucella abortus protein exhibiting lectin-like activity. Infection and Immunity 74(1): 183-191.

Vilches-Moure J,  Ramos-Vara JR (2004)  Immunohistochemical comparison of mouse and rabbit monoclonal antibodies in canine tissues.  Merck-Merial Summer Symposium.  Auburn, AL

 

 

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